KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MELK
All Species:
39.7
Human Site:
Y97
Identified Species:
62.38
UniProt:
Q14680
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14680
NP_055606.1
651
74642
Y97
P
G
G
E
L
F
D
Y
I
I
S
Q
D
R
L
Chimpanzee
Pan troglodytes
XP_001168921
651
74605
Y97
P
G
G
E
L
F
D
Y
I
I
S
Q
D
R
L
Rhesus Macaque
Macaca mulatta
XP_001115076
651
74642
Y97
P
G
G
E
L
F
D
Y
I
I
S
Q
D
R
L
Dog
Lupus familis
XP_538730
651
74149
Y97
P
G
G
E
L
F
D
Y
I
I
S
Q
D
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61846
643
72695
Y97
P
G
G
E
L
F
D
Y
I
I
S
Q
D
R
L
Rat
Rattus norvegicus
P54645
559
63955
G34
Y
I
L
G
D
T
L
G
V
G
T
F
G
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509217
655
73776
Y99
P
G
G
E
L
L
D
Y
I
V
S
K
A
R
L
Chicken
Gallus gallus
NP_001026680
657
74208
Y99
P
G
G
E
L
F
D
Y
I
V
S
K
D
R
L
Frog
Xenopus laevis
NP_001081569
651
74289
Y99
P
G
G
E
L
F
D
Y
I
I
A
K
D
R
L
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
H146
S
G
G
E
I
F
D
H
L
V
A
H
G
R
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395000
606
68302
H81
Q
V
I
E
T
E
S
H
Y
F
M
V
I
E
Y
Nematode Worm
Caenorhab. elegans
NP_001023420
703
79966
Y97
S
G
G
E
M
F
D
Y
I
V
R
K
E
R
L
Sea Urchin
Strong. purpuratus
XP_781767
971
109658
Y373
P
G
G
E
L
F
D
Y
I
V
A
K
D
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q2V452
441
50581
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
M96
K
V
L
A
K
S
D
M
Q
G
R
I
E
R
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.4
91.7
N.A.
83.4
29.6
N.A.
70.8
61.7
66.2
20.2
N.A.
N.A.
39.9
37.9
32.7
Protein Similarity:
100
99.5
97.5
95.8
N.A.
90.3
47.4
N.A.
80.1
75.9
80.3
34.1
N.A.
N.A.
55.7
56
45.5
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
73.3
86.6
86.6
40
N.A.
N.A.
6.6
60
80
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
86.6
100
100
80
N.A.
N.A.
13.3
86.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.8
27
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
47.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
0
0
20
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
80
0
0
0
0
0
54
0
0
% D
% Glu:
0
0
0
80
0
7
0
0
0
0
0
0
14
7
7
% E
% Phe:
0
0
0
0
0
67
0
0
0
7
0
7
0
0
0
% F
% Gly:
0
74
74
7
0
0
0
7
0
14
0
0
14
0
0
% G
% His:
0
0
0
0
0
0
0
14
0
0
0
7
0
0
0
% H
% Ile:
0
7
7
0
7
0
0
0
67
40
0
7
7
0
0
% I
% Lys:
7
0
0
0
7
0
0
0
0
0
0
34
0
7
0
% K
% Leu:
0
0
14
0
60
7
7
0
7
0
0
0
0
0
67
% L
% Met:
0
0
0
0
7
0
0
7
0
0
7
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
7
0
0
34
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
14
0
0
80
0
% R
% Ser:
14
0
0
0
0
7
7
0
0
0
47
0
0
0
0
% S
% Thr:
0
0
0
0
7
7
0
0
0
0
7
0
0
0
0
% T
% Val:
0
14
0
0
0
0
0
0
7
34
0
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
67
7
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _